Anti-NPTX2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10889-1-AP-150UL
10090-910EA 459.7 USD
10090-910
Anti-NPTX2 Rabbit Polyclonal Antibody
Antibodies
Neuronal pentraxins constitute a family of proteins that are homologous to C-reactive protein (CRP) and serum amyloid P component (SAP), including NPTX1, NPTX2, and the neuronal pentraxin receptor (NPTXR). NPTX2, also known as NARP (neuronal activity-regulated pentaxin), is secreted protein involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. NPTX2 is highly up-regulated in the Parkinson's disease (PD), suggesting it may be involved in the pathology of PD.

Western Blot: Mouse Brain Tissue, 1:200-1:2000; IHC: Human pancreas cancer Tissue, 1:20-1:200

Type: Primary
Antigen: NPTX2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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