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Anti-REC8 Rabbit Polyclonal Antibody

Supplier: Proteintech
REC8, also named as Rec8p and REC8L1, belongs to the rad21 family. This cohesin protein is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II. Rec8 is present in an unphosphorylated form early in meiotic prophase but is phosphorylated prior to meiosis I. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human REC8. This antibody can recognize the monomeric, non-phosphorylated form(63-70kd) of REC8 and other forms(80-100kd) which represent either posttranslationally modified forms or alternative transcript products. .

Western Blot: Human Testis Tissue, 1:500-1:5000

Type: Primary
Antigen: REC8
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10793-1-AP 10093-486 Each (150µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol REC8
Antigen Name REC8 Meiotic Recombination Protein
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
Antigen Synonyms Kleisin-Alpha, Meiotic Recombination And Sister Chromatid Cohesion Phosphoprotein Of The Rad21p Family, REC8-Like 1, Recombination And Sister Chromatid Cohesion Protein Homolog, REC8L1, Meiotic Recombination Protein REC8-Like 1
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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