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Anti-Ku70 Rabbit Polyclonal Antibody

Supplier: Proteintech
10723-1-AP
X-ray repair cross-complementing protein 6(XRCC6)gene encodes subunit p70 of the p70/p80 autoantigen which has a role in DNA repair or transposition. DNA helicase II complex binds preferentially to fork-like ends of double-standed DNA in a cell cycle-dependent manner, which may be mediated by XRCC6. XRCC6/5 can form a heterdimer, which function as a regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA, and also it can stablize broken DNA ends and bringing them together. Otherwise, XRCC5/6 heterdimer together with APEX1 can negatively regulate of transcription.

Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; FC: HepG2 Cells, N/A; IP: HeLa Cells, 1:500-1:5000

Type: Primary
Antigen: Ku70
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10723-1-AP 10088-746 Each (150µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol Ku70
Antigen Name 5'-deoxyribose-5-phosphate lyase Ku70
Reactivity Rat, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen Synonyms 70 kDa subunit, 5'-dRP lyase Ku70, thyroid, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, lupus Ku autoantigen protein p70, thyroid autoantigen 70kD (Ku antigen), ATP-dependent DNA helicase II 70 kDa subunit, 70kDa,X-ray repair cross-complementing protein 6, ATP-dependent DNA helicase II, DNA repair protein XRCC6, Ku autoantigen p70 subunit, Ku autoantigen, 70 kDa subunit of Ku antigen, 5'-deoxyribose-5-phosphate lyase Ku70
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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