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Anti-DLK1 Rabbit Polyclonal Antibody

Supplier: Proteintech
DLK1, also named PREF1, FA1, or pG2, is a transmembrane protein belonging to the epidermal growth factor (EGF)-like superfamily . It contains six EGF-like repeats in the extracellular region. DLK1 is abundant in preadipocytes and regulate adipocyte differentiation negatively . Deficiency of DLK1 gives rise to growth retardation and accelerated adiposity in mouse model. Expression of DLK1 is found in tumors with neuroendocrine features that implies DLK1 may be involved in neuroendocrine differentiation . It has been reported overexpression of DLK1 could lead to the development of metabolic abnormalities by impairment of adipocyte function in mice . The gene of DLK1 maps to chromosome 14q32, and encodes a 383-amino acid protein with a calculated molecular mass of 41 kDa. In preadipocytes, multiple discrete forms of DLK1 protein of 45-60 kDa are present, owing in part to N-linked glycosylation .

Western Blot: Mouse Placenta Tissue, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200

Type: Primary
Antigen: DLK1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10636-1-AP 10085-900 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol DLK1
Antigen Name Delta-like 1 Homolog (Drosophila)
Reactivity Mouse, Human, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
Antigen Synonyms Protein Delta Homolog 1, Pref-1, ZOG, PREF1, DLK-1, pG2, Preadipocyte Factor 1, Fetal Antigen 1, Delta1, FA1, DLK
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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