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Anti-RBM15 Rabbit Polyclonal Antibody

Supplier: Proteintech
10587-1-AP
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.

Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human breast cancer, 1:20-1:200; IF: HepG2, 1:20-1:200

Type: Primary
Antigen: RBM15
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10587-1-AP 10093-396 Each (150µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol RBM15
Antigen Name RNA Binding Motif Protein 15
Reactivity Mouse, Rat, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Antigen Synonyms RBM15_HUMAN., One twenty two protein, RNA binding mot protein 15, OTT, SPEN, OTT1
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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