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Anti-MPZ,P0 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-MPZ,P0 Rabbit Polyclonal Antibody

Anti-MPZ,P0 Rabbit Polyclonal Antibody

Anti-MPZ,P0 Rabbit Polyclonal Antibody

Anti-MPZ,P0 Rabbit Polyclonal Antibody

10572-1-AP-150UL

10090-402EA 459.7 USD

10090-402

Anti-MPZ,P0 Rabbit Polyclonal Antibody

Antibodies

MPZ (myelin protein zero), also known as P0, a transmembrane glycoprotein (~30 kDa), is a member of the immunoglobulin supergene family. Synthesized by myelin-forming Schwann cells, MPZ is the major structural protein component of myelin in the peripheral nervous system. It is involved in formation and maintenance of compact myelin, and plays a role in the creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae. More than 120 mutations detected in the gene of MPZ cause various forms of hereditary neuropathy, which include Charcot-Marie-Tooth disease type 1B (CMT1B), CMT2, Dejerine-Sottas syndrome (DSS), and congenital hypomyelination neuropathy (CHN). This antibody can recognize endogenous MPZ, and can be used as a marker of myelinating Schwann cells.

Western Blot:Schwann Cells, 1:200-1:2000; IF: Myelinating SCs Cells, 1:20-1:200

Type: Primary
Antigen: MPZ,P0
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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