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Anti-PSME1 Rabbit Polyclonal Antibody

Supplier: Proteintech
The principal function of the proteasome is targeted degradation of intracellular proteins. Activity of the 20S proteasome is controlled by regulatory complexes that bind to the ends of the cylindrical proteasome. 11S regulator (REG or PA28), is a complex of 28 kDa subunits that is thought to activate proteasomes toward the production of antigenic peptides. Human PSME1 and PSME2 genes encode the two proteasome activators PA28 alpha and beta, respectively, which have been implicated in antigen processing for loading class I MHC molecules. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Western Blot: Mouse spleen Tissue, 1:200-1:2000

Type: Primary
Antigen: PSME1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10543-1-AP 10092-988 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol PSME1
Antigen Name Proteasome (prosome, macropain) Activator Subunit 1 (PA28 alpha)
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
Antigen Synonyms interferon-gamma IEF SSP 5111, 29-kD MCP activator subunit, IFI5111, proteasome activator subunit-1, PA28A, proteasome (prosome, interferon gamma up-regulated I-5111 protein, REGalpha , PSME1, PA28alpha, 11S regulator complex alpha subunit, proteasome activator subunit 1, interferon-gamma-inducible protein 5111, macropain) activator subunit 1 (PA28 alpha), MGC8628, activator of multicatalytic protease subunit 1
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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