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Anti-LY6C1 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: RB6-8C5]

Supplier: Tonbo Biosciences

The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

The RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200.

Type: Primary
Antigen: LY6C1
Clonality: Monoclonal
Clone: RB6-8C5
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg 20-5931-U100 10050-644 Each (100µG) Retrieving Restricted
25 µg 20-5931-U025 10050-642 Each (25µG) Retrieving Restricted
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SPECIFICATIONS

Antibody Type Primary
Antigen Name Lymphocyte Antigen 6 Complex, locus C1
Antigen Symbol LY6C1
Antigen Synonyms Ly6c, AA959465, AA682074, Ly-6C1, Ly-6C Ly6c, AA959465, Ly-6C1, AA682074, Ly-6C
Clonality Monoclonal
Clone RB6-8C5
Conjugation APC (Allophycocyanin)
Flow Cytometry Yes
Gene ID 17067
Host Rat
Isotype IgG2b
Neutralization Yes
Reactivity Mouse
Storage Temperature Store undiluted at 2-8°C, protect from light, do not freeze.
Tested Applications Flow Cytometry
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