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VEGF Recombinant Protein, ProSci Inc

Supplier: Prosci
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

Store in working aliquots at -20°C. Avoid freeze/thaw cycles.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.002 mg 40-491 10072-590 Each (2µG) Retrieving
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SPECIFICATIONS

Protein/Peptide Name VEGF
Protein Synonyms Vascular endothelial growth factor A, Vpf, Vegf, VEGF-A, Vascular permeability factor
Protein/Peptide Type Recombinant
Species Mouse
Source E. coli
Purity >98%
Formulation Lyophilized
Biological Activity Biological activity was determined by the dose - dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0 - 5.0 ng/mL.
Protein Type Recombinant
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