Anti-IRF3 Rabbit Polyclonal Antibody

Supplier: Prosci

10079-376EA 582.9 USD
Anti-IRF3 Rabbit Polyclonal Antibody
Interferon regulatory factor 3 (IRF3) is a trascription factor activated in response to various environmental stresses including viral infection and DNA-damaging agents. IRF3 can inhibit cell growth and plays a critical role in controling the expression of genes in the innate immune response. In unstimulated cells, IRF3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF3, leading to its translocation to the nucleus, where it activates promoters Suitable for use in Western Blot and Immunohistochemistry (FFPE). Other applications not tested. Detects endogenous levels of human IRF3 at 57kD. Species Crossreactivity: monkey.

IRF3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 ?g/mL.

10 mM sodium HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/mL BSA, 50% glycerol.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: IRF3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Monkey
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