Anti-RARB Mouse Monoclonal Antibody [clone: 336]

Supplier: Prosci

50-177
10075-450EA 582.92 USD
10075-450
Anti-RARB Mouse Monoclonal Antibody [clone: 336]
Antibodies
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with canine, guinea pig, mouse and rat tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Protein G purified

100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: RARB
Clonality: Monoclonal
Clone: 336
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat, Dog, Goat
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