Anti-NTRK1 Rabbit Polyclonal Antibody

Supplier: Prosci

10076-574EA 582.9 USD
Anti-NTRK1 Rabbit Polyclonal Antibody
NTRK1 (trkA), a Trk/Ror type protein kinase, is a high-affinity receptor for the nerve growth factor NGF. NTRK1 has been shown to regulate neural development and maintenance of neural network. Mutation in NTRK1 gene is responsible for congenital insensitivity to pain with anhidrosis (CIPA), an autosomal recessive hereditary disorder characterized by recurrent episodic fever, anhidrosis (inability to sweat), absence of reaction to noxious stimuli, self-mutilating behavior, and mental retardation. Rearrangements and fusion of NTRK1 gene to other genes have been implicated in colon and papillary thyroid cancers. Two protein isoforms have been identified.

NTRK1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

Affinity Chromatography

PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: NTRK1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human, Mouse, Rat
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