Anti-P4HB Rabbit Polyclonal Antibody

Supplier: Prosci

49-878
10076-560EA 680.04 USD
10076-560
Anti-P4HB Rabbit Polyclonal Antibody
Antibodies
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

P4HB antibody can be used in immunohistochemistry starting at 10 ?g/mL.

Supplied as a liquid in 10 mM sodium HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/mL BSA, 50% glycerol.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: P4HB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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