Anti-GLI3 Rabbit Polyclonal Antibody

Supplier: Prosci

49-600
10079-076EA 593.09 USD
10079-076
Anti-GLI3 Rabbit Polyclonal Antibody
Antibodies
Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-poly-syndactyly syndrome (GCPS); an autosomal dominant disorder-affecting limb and cranio-facial development. Two isoforms of human Gli-3 have been reported. One is the full-length protein at ~170-190 kDa and the other is a truncated isoform at ~80 kDa.

GLI3 antibody can be used in immunohistochemistry starting at 5 ?g/mL, and immunofluorescence.

0.02 M potassium phosphate, 0.15 M NaCl, pH 7.2, 0.1% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: GLI3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Squirrel monkey, Chimpanzee, Chicken, Dog, Xenopus, Human, Quail
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