Anti-TLR8 Rabbit Polyclonal Antibody

Supplier: Prosci

49-494
10079-032EA 582.9 USD
10079-032
Anti-TLR8 Rabbit Polyclonal Antibody
Antibodies
TLR8 (Toll Like Receptor 8). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).

TLR8 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 ?g/mL.

0.02 M potassium phosphate, 0.15 M NaCl, pH 7.2, 0.01% sodium azide.

TLR8 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C. As with all antibodies avoid freeze/thaw cycles. Store undiluted.

Type: Primary
Antigen: TLR8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse
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