Anti-CXCR4 Mouse Monoclonal Antibody

Supplier: Prosci

49-232
10074-490EA 561.89 USD InStock
10074-490
Anti-CXCR4 Mouse Monoclonal Antibody
Antibodies
CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.

CXCR4 antibody can be used in immunohistochemistry starting at 10 ?g/mL.

Affinity Chromatography

PBS, pH 7.2, 0.09% sodium azide.

Aliquot and store at 4ºC. Avoid freezing.

Type: Primary
Antigen: CXCR4
Clonality: Monoclonal
Clone: [12G5]
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Baboon, Chimpanzee, Human, Monkey
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