Anti-CDK4 Rabbit Polyclonal Antibody

Supplier: Prosci

10078-692EA 582.9 USD
Anti-CDK4 Rabbit Polyclonal Antibody
CDK4, a CDC2/CDK-type protein kinase, regulates cell cycle G1 phase progression. CDK4 associates with and is regulated by D-type cyclins and the CDK inhibitor p16 (CDKN2A). Two alternatively spliced variants have been reported. CDK4 has been shown to phosphorylate the retinoblastoma protein, and mutations in the CDK4 gene have been linked to tumorigenesis in several types of cancers, including cutaneous malignant melanoma.

CDK4 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.

Affinity Chromatography

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% gelatin.

Store CDK4 antibody undiluted at 4 °C. Do not freeze.

Type: Primary
Antigen: CDK4
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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