JNK2, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK2 is phosphorylated by by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK2 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four distinct isoforms, resulting from alternatively spliced transcript variants, have been reported - three different isoforms comprised of 382 amino acids and one comprised of 424 amino acids.
MAPK9 antibody can be used in Western Blot starting at 2 ?g/mL, immunohistochemistry starting at 5 ?g/mL, immunocytochemistry, and immunoprecipitation
PBS, 0.01% sodium azide, 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: MAPK9
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human