Anti-MTA2 Rabbit Polyclonal Antibody

Supplier: Prosci

48-911
10076-084EA 582.9 USD
10076-084
Anti-MTA2 Rabbit Polyclonal Antibody
Antibodies
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. The transcriptional activity of p53 is modulated by protein stability and acetylation. PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.

MTA2 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 ?g/mL, and immunofluorescence starting at 10 ?g/mL.

PBS, 0.2% gelatin, 0.05% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: MTA2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Bovine, Chimpanzee, Dog, Xenopus, Human, Monkey, Mouse, Rat
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