Anti-FXR2 Mouse Monoclonal Antibody [clone: [1G2]]

Supplier: Prosci

48-845
10078-384EA 582.9 USD
10078-384
Anti-FXR2 Mouse Monoclonal Antibody [clone: [1G2]]
Antibodies
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins. FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. FXR2 associates with polyribosomes, predominantly with 60S large ribosomal subunits. It may self-associate or interact with FMRP and FXR1. FXR2 may have a role in the development of fragile X mental retardation syndrome.

FXR2 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 ?g/mL.

Ascites, 0.1% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: FXR2
Clonality: Monoclonal
Clone: [1G2]
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse
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