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Anti-NEK9 Rabbit Polyclonal Antibody

Immunohistochemistry staining of NEK9 in brain cortex tissue using NEK9 Antibody.

Immunohistochemistry staining of NEK9 in brain cortex tissue using NEK9 Antibody.

48-790

10076-040EA 674.53 USD

10076-040

Anti-NEK9 Rabbit Polyclonal Antibody

Antibodies

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro.

NEK9 antibody can be used in immunohistochemistry starting at 10 ?g/mL, immunofluorescence, immunoprecipitation, and flow cytometry.

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: NEK9
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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