Anti-MAPK14 Rabbit Polyclonal Antibody

Supplier: Prosci

10076-034EA 582.9 USD
Anti-MAPK14 Rabbit Polyclonal Antibody
MAP kinase p38 alpha, a MAPK type protein kinase, is an environmental stress- and inflammatory cytokine-induced kinase that is associated with the regulation of gene expression, cell proliferation and cell death. p38alpha is phosphorylated by MEK3/MAP2K3 or MKK6/MAP2K6. Activated p38alpha either remains in the cytosol, where it phosphorylates cytosolic proteins including MNK1/2, PLA2 and PRAK, or translocates to the nucleus, where it phosphorylates several substrates, including ATF2, CHOP/GADD153, MAPKAPK-2 and -3, MEF2-A and -C, MSK, Myc binding partner Max and Sap-1a. At least four protein isoforms, resulting from alternatively spliced transcript variants of this gene, have been identified - 297, 307 and two isoforms of 360 amino acids with differing internal segments.

MAPK14 antibody can be used in ELISA, Western Blot starting at 1:1000 - 1:2000, and immunohistochemistry starting at 10 ?g/mL.

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.1% gelatin.

Aliquot and store at 4ºC. Avoid freezing.

Type: Primary
Antigen: MAPK14
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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