Anti-AKT2 Rabbit Polyclonal Antibody

Supplier: Prosci

10078-110EA 624.31 USD
Anti-AKT2 Rabbit Polyclonal Antibody
AKT2 encodes a RAC/AKT-type protein kinase that contains a N-terminal pleckstrin-homology (PH) domain and a central catalytic domain closely related to both cAMP-dependent protein kinase and protein kinase C. The protein is a member of PI3K-mediated signalling pathways associated with the regulation of proliferation, survival, protein synthesis, and metabolism. It is activated by a variety of growth factors. AKT2 has been shown to be transcriptionally regulated by MyoD and to activate MyoD-myocyte enhancer binding factor-2 (MEF2) transactivation activity during muscle differentiation. Glycogen synthase kinase 3 (GSK-3) also has been shown to be a downstream target of AKT2. The AKT2 gene is one of the human homologues of v-akt, the transduced oncogene of the AKT8 virus, which induces lymphomas in mice. It has been implicated in breast, ovarian, and pancreatic cancers.

AKT2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.

PBS, 0.05% sodium azide.

Aliquot and store at 4°C. Avoid freezing.

Type: Primary
Antigen: AKT2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human, Mouse, Rat
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