Anti-WNK1 Rabbit Polyclonal Antibody

Supplier: Prosci

10077-976EA 561.89 USD InStock
Anti-WNK1 Rabbit Polyclonal Antibody
WNK1, a WNK type protein kinase, contains a small N-terminal domain followed by a kinase domain and a long C-terminal tail. The protein is cytoplasmic and has been shown to regulate both the c-Jun N-terminal kinase pathway and the actin cytoskeleton in vitro. WNK1 has been identified as the gene mutant in pseudohypoaldosteronism type 2, also known as Gordon hyperkalemia-hypertension syndrome, which is a rare autosomal dominant form of volume-dependent, low-renin hypertension. Disease-causing mutations are large intronic deletions that increase WNK1 expression. At least two variants of WNK1 are produced by alternative splicing.

WNK1 antibody can be used in immunohistochemistry starting at 6 μg/mL.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: WNK1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Bat, Gibbon, Bovine, Chicken, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
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