Anti-TRAF2 And NCK Interacting Kinase Rabbit Polyclonal Antibody

Supplier: Prosci

48-330
10077-968EA 582.9 USD
10077-968
Anti-TRAF2 And NCK Interacting Kinase Rabbit Polyclonal Antibody
Antibodies
TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when overexpressed in Phoenix-A cells, and this activation is mediated solely by the C-terminal germinal center kinase homology region. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. At least eight splice isoforms have been reported.

TNIK antibody can be used in immunohistochemistry starting at 15 - 20 ?g/mL.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: TNIK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Bat, Gibbon, Gorilla, Human, Monkey, Rabbit
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