Anti-SGK3 Rabbit Polyclonal Antibody

Supplier: Prosci

10077-954EA 582.9 USD
Anti-SGK3 Rabbit Polyclonal Antibody
SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro.

SGK3 antibody can be used in immunohistochemistry starting at 10 - 15 ?g/mL.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: SGK3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human
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