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Anti-ADAMTS4 Rabbit Polyclonal Antibody

Immunohistochemistry staining of ADAMTS4 in heart tissue using ADAMTS4 Antibody.

Immunohistochemistry staining of ADAMTS4 in heart tissue using ADAMTS4 Antibody.

48-124

10077-754EA 684.46 USD

10077-754

Anti-ADAMTS4 Rabbit Polyclonal Antibody

Antibodies

ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease.

ADAMTS4 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 ?g/mL, and immunofluorescence starting at 10 ?g/mL.

PBS, 0.1% sodium azide.

Aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: ADAMTS4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Gibbon, Dog, Horse, Human, Orangutan

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