Anti-SERPINB5 Rabbit Polyclonal Antibody (Biotin)

Supplier: Prosci

10098-006EA 420.98 USD
Anti-SERPINB5 Rabbit Polyclonal Antibody (Biotin)
Maspin was discovered as a mammary tumor suppressor that is expressed in normal mammary epithelium but lost in most breast cancer cell lines. While maspin is related to the serpin family of serine protease inhibitors, it may not function as a protease inhibitor. It plays an essential role in embryonic development through critical roles in cell adhesion. While the precise mechanism of maspin signaling is unclear, the tumor suppressing activity of maspin has been attributed to its ability to inhibit cell invasion/metastasis and angiogenesis, while promoting apoptosis. Nuclear translocation of active IKKbeta has been shown to repress maspin transcription and promote prostate cancer metastasis.


The reconstituted antibody can temporarily be stored at 2-8°C. Long term storage at -20°C or below. Avoid repeated freeze-thaw cycles.

Type: Primary
Antigen: SERPINB5
Clonality: Polyclonal
Conjugation: Biotin
Host: Rabbit
Reactivity: Human
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