Anti-BMP7 Rabbit Polyclonal Antibody

Supplier: Prosci
38-135
10098-258EA 576.13 USD
10098-258
Anti-BMP7 Rabbit Polyclonal Antibody
Antibodies
BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.

Neutralization:<br>To yield one-half maximal inhibition [ND50] of the biological activity of Human BMP-7 (100 ng/mL), a concentration of 0.4-0.6 ?g/mL of this antibody is required.<br><br>ELISA:<br>Indirect:<br>To detect hBMP-7 by indirect ELISA (using 100 ?L/well antibody solution) a concentration of 0.5 - 2.0 ?g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hBMP-7.<br><br>Sandwich<br>To detect hBMP-7 by sandwich ELISA (using 100 ?L/well antibody solution) a concentration of 0.5 - 2.0 ?g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Human BMP-7 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hBMP-7. <br><br>Western Blot:<br>To detect hBMP-7 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ?g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hBMP-7 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

The reconstituted antibody can temporarily be stored at 2-8°C. Long term storage at -20°C or below. Avoid repeated freeze-thaw cycles.

Type: Primary
Antigen: BMP7
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
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