Anti-FBLN5 Mouse Monoclonal Antibody [clone: 3F8D5]

Supplier: ProSci
32-156
10070-566EA 486.37 USD
10070-566
Anti-FBLN5 Mouse Monoclonal Antibody [clone: 3F8D5]
Antibodies
Fibulin 5(FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Western Blot:1:500 - 1:2000 <br>ELISA:Propose dilution 1:10,000.<br>Determining optimal working dilutions by titration test.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: FBLN5
Clonality: Monoclonal
Clone: 3F8D5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgM
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR