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Anti-BCL10 Antibody [clone: 151]

Supplier: Diagnostic BioSystems

MOB442-05 MOB442

95024-248EA 327.92 USD

95024-248 99991-488

Anti-BCL10 Antibody [clone: 151]

Antibodies

Monoclonal anti-bcl-10 reacts specifically with human bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human bcl-10 molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (caspase recruitment domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of bcl-10 expression was also demonstrated to be involved in cellular oncogenesis.

Type:
Antigen: BCL10
Clonality:
Clone: 151
Conjugation:
Epitope:
Host: 0
Isotype:
Reactivity: 0

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