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Anti-PAK6 Rabbit Polyclonal Antibody

Supplier: Prosci

Anti-PAK6 Rabbit Polyclonal Antibody

Anti-PAK6 Rabbit Polyclonal Antibody

Anti-PAK6 Rabbit Polyclonal Antibody

Anti-PAK6 Rabbit Polyclonal Antibody

Anti-PAK6 Rabbit Polyclonal Antibody

Anti-PAK6 Rabbit Polyclonal Antibody

3073

89415-560EA 531.09 USD

89415-560

Anti-PAK6 Rabbit Polyclonal Antibody

Antibodies

PAK6 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.

Type: Primary
Antigen: PAK6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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