Casein Kinase II (CKII), New England Biolabs

Supplier: New England Biolabs (NEB)
P6010S P6010L P6010S P6010L
101641-528EA 153.75 USD InStock
CA101641-528 CA101641-526 101641-528 101641-526
Casein Kinase II (CKII), New England Biolabs
Casein Kinase II (CK2) is a constitutively active serine/threonine protein kinase composed of two 44 kDa catalytic α-subunits and two 26 kDa regulatory β-subunits in an α2β2 configuration to form stable heterotetramers

CK2 holoenzyme undergoes autophosphorylation at two serine residues (S2/S3) of its β-subunit. Recently it has been shown that CK2 α-subunits undergo intermolecular tyrosine-autophosphorylation at Y182, which may represent a specific regulatory mechanism. Also, CK2 is able to phosphorylate, under special circumstances, tyrosyl residues in proteins. CK2 is implicated in a variety of cellular functions.
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