SP Sepharose™ XL Ion Exchange Chromatography Media, GE Healthcare

Supplier: GE Healthcare - Life Sciences
17-5073-01 17-5073-01
89128-874EA 698.07 USD InStock
89128-874 CA89128-874
SP Sepharose™ XL Ion Exchange Chromatography Media, GE Healthcare
Protein Purification Media
SP Sepharose XL is based on a highly cross-linked, bead formed 6% agarose matrix similar to the well established SP Sepharose Fast Flow media

  • High loading capacities give more productive capture from clarified feedstocks
  • Strong cation exchanger designed for capture steps
  • High chemical stability for effective CIP/sanitization
  • Sulphopropyl ligand, dextran extenders through ether bonds coupling method

The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool. With its high loading capacities and excellent physical and chemical stability, SP Sepharose XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples. As member of the BioProcess media range, SP Sepharose XL meets industrial demands with security of supply and comprehensive technical and regulatory support.

Dextran chains are covalently coupled to the agarose matrix and modified with sulphopropyl (SP) strong cation exchange groups through chemically stable ether bonds. The stable agarose matrix and long, flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates
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