Etoposide ≥98% (by HPLC)

Supplier: ADIPOGEN CORP MS
Danger

Synonyms: (5R,5aR,8aR,9S)-9-(((4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one4'-Demethylepipodophyllotoxin 9-(4,6-O-Ethylidene-beta-D-glucopyranoside)

AG-CR1-3572-M100 AG-CR1-3572-5100 AG-CR1-3572-M025
102516-332EA 90 USD
102516-332 102516-334 102516-330
Etoposide ≥98% (by HPLC)
Etoposide

Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcription and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells

Formula: C₂₉H₃₂O₁₃
MW: 588.56 g/mol
Storage Temperature: Ambient
MDL Number: MFCD00869325
CAS Number: 33419-42-0

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Specification Test Results

Source/Host Semisynthetic derivative of podophyllotoxin.
Purity 98% (HPLC)
Appearance/Color White to off-white powder.
Solubility Soluble in DMSO, ethanol, methanol or dimethylformamide.

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