Cyclopamine ≥98%
Supplier: ADIPOGEN CORP MS
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Warning
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AG-CN2-0028-M005
AG-CN2-0028-M001
102515-774EA
83.08
USD
102515-774
102515-772
Cyclopamine ≥98%
Cyclopamine
Cell permeable steroidal alkaloid. Specific sonic hedgehog (Shh) signaling pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer.
Formula:
C₂₇H₄₁NO₂ Storage Temperature: Freezer |
MDL Number:
MFCD09878269 CAS Number: 4449-51-8 |
Specification Test Results
Source/Host | Isolated from Veratrum californicum. |
Purity |
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Appearance/Color | White to off-white solid. |
Solubility | Soluble in ethanol, methanol, DMF or DMSO. Insoluble in water. |
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