Cyclopamine ≥98%

Supplier: ADIPOGEN CORP MS
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AG-CN2-0028-M005 AG-CN2-0028-M001
102515-774EA 83.08 USD
102515-774 102515-772
Cyclopamine ≥98%
Cyclopamine

Cell permeable steroidal alkaloid. Specific sonic hedgehog (Shh) signaling pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer.

Formula: C₂₇H₄₁NO₂
Storage Temperature: Freezer
MDL Number: MFCD09878269
CAS Number: 4449-51-8

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Specification Test Results

Source/Host Isolated from Veratrum californicum.
Purity 98%
Appearance/Color White to off-white solid.
Solubility Soluble in ethanol, methanol, DMF or DMSO. Insoluble in water.

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