Rapamycin (from Streptomyces hygroscopicus) ≥98%Supplier: ADIPOGEN CORP MS
Rapamycin is an antibiotic with anti-bacterial and anti-fungal properties.
- Blocks activation of T and B cells
- Potent immunosuppressant
- Apoptosis enhancer
Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition. Anti-proliferative. Antitumor compound. Activator of autophagy both in vitro and in vivo. Anti-HIV and anti-aging compound. Neuroprotective. Suppressor for self-renewal and vascular differentiation potential in hemangioma stem cells.
White to off-white solid
Stable for at least two years after receipt when stored at -20°C.
Soluble in DMSO, methanol or chloroform.
MW: 914.19 g/mol
Storage Temperature: Freezer
CAS Number: 53123-88-9