Rapamycin (from Streptomyces hygroscopicus) ≥98%


AGCN20025M025 AGCN20025M005 AGCN20025C100 AGCN20025M001
102515-762EA 221.54 USD InStock
102515-762 102515-760 102515-756 102515-758
Rapamycin (from Streptomyces hygroscopicus) ≥98%

Rapamycin is an antibiotic with anti-bacterial and anti-fungal properties.

  • Blocks activation of T and B cells
  • Potent immunosuppressant
  • Apoptosis enhancer

Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition. Anti-proliferative. Antitumor compound. Activator of autophagy both in vitro and in vivo. Anti-HIV and anti-aging compound. Neuroprotective. Suppressor for self-renewal and vascular differentiation potential in hemangioma stem cells.

White to off-white solid

Stable for at least two years after receipt when stored at -20°C.

Soluble in DMSO, methanol or chloroform.

Formula: C₅₁H₇₉NO₁₃
MW: 914.19 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00867594
CAS Number: 53123-88-9

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