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(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride ≥95% (by TLC)

Supplier: Enzo Life Sciences
Synonyms: Nalpha-p-Tosyl-L-lysine chloromethyl ketone hydrochlorideTLCKTos-Lys-chloromethylketone·HCl

Inhibitor of trypsin and trypsin-like proteases

Irreversible inhibitor of trypsin and trypsin-like serine proteases such as granzyme D and tryptase. Also inhibits other proteases including plasmin, thrombin, and papain and some kinases including PKC. Inhibits LPS-induced expression of COX-2 in macrophages. Inhibits apoptosis (possibly through the inhibition of serine proteases). Chymotrypsin is not inhibited by TLCK, so this inhibitor can be used to block contaminating trypsin activity in chymoptrypsin preparations. TLCK can be used in combination with a chymotrypsin inhibitor to prevent proteolytic degradation during the isolation of proteins.

Formula: C₁₄H₂₂Cl₂N₂O₃S
MW: 369.301 g/mol
MDL Number: MFCD00065395
CAS Number: 4272-74-6



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Size Supplier No. VWR Catalog Number Unit Price Quantity
200 mg BML-PI121-0200 89161-616 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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