Phosphoramidon

Supplier: Enzo Life Sciences
BML-PI111-0025 BML-PI111-0005
89161-594EA 916.97 USD
89161-594 89161-592
Phosphoramidon
Proteins and Peptides
Neprilysin inhibitor

Inhibits neutral endopeptidase 24.11 (NEP, neprilysin; EC 3.4.24.11) (Ki=2nM), a cell surface zinc metalloprotease which cleaves bioactive peptides such as bradykinin, neurotensin, and enkephalin. Also inhibits neprilysin 2 (Ki~2nM). Potent inhibitor of endothelin-converting enzyme (ECE) (IC50=0.68μM).
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