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clasto-Lactacystin β-Lactone ≥95% (by HPLC)

Supplier: Enzo Life Sciences
Synonyms: Omuralide

Highly specific, cell permeable, and irreversible 20S proteasome inhibitor. Inhibits ubiquitin proteasome pathway in cell culture (IC50=1µM). It has been suggested that the natural product lactacystin acts as a precursor for clasto-lactacystin β-lactone and that the latter is the sole species that interacts with the proteasome. Inhibits cathepsin A. Leads to a reduction of adipogenesis. Induces neurite growth and inhibits cell cycle progression. 

  • Proteasome inhibitor

White solid.

Soluble in DMSO (25mg/ml) or acetonitrile.

Formula: C10H15NO4
MW: 213,2
Storage Temperature: Freezer
CAS Number: 155975-72-7



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg BML-PI108-0100 89161-586 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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