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NF-κB SN50 Cell Permeable Inhibitory Peptide, Enzo Life Sciences

Supplier: Enzo Life Sciences
Inhibits NF-kappaB translocation

Sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-kappaB p50 linked to a peptide cell-permeablization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). Peptide inhibits translocation of the NF-kappaB active complex into the nucleus. In mouse endothelial LE-II cells induced with LPS, inhibition of NF-kappaB nuclear translocation was 88% at 50µg/ml (18 µM). In human monocytic THP-1 cells induced by LPS or TNFalpha there was 85% inhibition at 100µg/ml. Sold under license from Vanderbilt University.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg BML-P600-0005 89161-280 Each Retrieving Restricted

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Protein/Peptide Name NF-κB SN50 Cell Permeable Inhibitory Peptide
Purity ≥97% (HPLC)
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