Gambogic amide ≥98% (by TLC)

Supplier: Enzo Life Sciences
Danger

BML-N159-0005 BML-N159-0001
89160-606EA 475.04 USD
89160-606 89160-604
Gambogic amide ≥98% (by TLC)
Gambogic amide

TrkA ligand


A novel small molecule NGF mimic discovered using a cell-based chemical genetic screen for TrkA agonists. Gambogic amide selectively binds to TrkA, triggers its tyrosine phosphorylation, elicits PI3-kinase/Akt and MAPK activation, provokes neurite outgrowth in PC12 cells and prevents neuronal cell death. EC50 for antiapoptotic activity is 5nM.


Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml).

Formula: C₃₈H₄₅NO₇
Melting Pt: 74…76 °C
Storage Temperature: Ambient
CAS Number: 286935-60-2

Order Now

Specification Test Results

Purity ≥98% (TLC)
Appearance Yellow-orange solid
Melting Point 74 - 76°C

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR