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SEW-2871 ≥98%

Supplier: Enzo Life Sciences
Synonyms: 5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole

BML-LP106-0050
SEW-2871 is a novel, potent EDG receptor agonist structurally unrelated to sphingosine-1-phosphate and is highly selective for the human S1P1 receptor. It inhibits lymphocyte recirculation in vivo and produces immunosuppression without associated bradycardia which is induced by other less selective S1P agonists. In mice SEW-2871 blocked TNFα induced monocyte adhesion to endothelium.

  • S1P receptor ligand

White solid.


Formula: C20H10F6N2OS
MW: 440,4
Storage Temperature: Ambient
CAS Number: 256414-75-2


 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
50 mg BML-LP106-0050 89160-556 Each Retrieving Restricted
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