Paxilline ≥97% (by HPLC)

Supplier: Enzo Life Sciences

BML-KC155-0025 BML-KC155-0005
89160-226EA 658.4 USD
89160-226 89160-224
Paxilline ≥97% (by HPLC)
Paxilline

K+ channel blocker


Paxilline is an indole alkaloid isolated from Penicillium paxilli. It is a selective and reversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (70% block at 10 nM). In neutrophils, Paxilline blockage of BKCa channels decreased the alkalinization of phagocytic vacuoles and inhibited the microbicidal process. Inhibitor of the cerebellar inositol 1,4,5-triphosphate (InsP(3)) receptor. 

Formula: C₂₇H₃₃NO₄
MDL Number: MFCD00083464
CAS Number: 57186-25-1
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