12(S)-Hydroperoxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (HPETE) ≥98%
Supplier: Enzo Life Sciences
Synonyms:
12(S)-HPETE
BML-HP012-0050
89160-096EA
416.14
USD
89160-096
12(S)-Hydroperoxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (HPETE) ≥98%
12(S)-Hydroperoxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (HPETE)
Primary metabolite of arachidonic acid via the 12-lipoxygenase pathway. Inhibits thromboxane synthase. Inhibits platelet aggregation via activation of guanylate cyclase (100% at 5µM). Stimulates leukotriene biosynthesis. Potent and selective inhibitor of Ca2+-calmodulin-dependent protein kinase II (IC50=0.7µM). Endogenous TRPV1 agonist (Ki=0.35µM).
- Thromboxane synthase inhibitor
Liquid.
Soluble in DMSO or dimethyl formamide; slightly soluble in PBS, pH 7.2 (0.8mg/ml) or 0.1M Na2CO3 (2mg/ml).
Formula:
C₂₀H₃₂O₄ MW: 336.5 g/mol Storage Temperature: Ultra-Low Temperature Freezer (–80°C) |
CAS Number:
71774-10-2 |
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