Mirin ≥95% (by TLC)
Supplier: Enzo Life Sciences
Synonyms:
cis-5-(4-Hydroxybenzylidene)-2-imino-4-thiazolidinone
BML-GR357-0025
BML-GR357-0005
89158-994EA
452.36
USD
89158-994
89158-992
Mirin ≥95% (by TLC)
Mirin
MRN inhibitor
The MRN-ATM pathway is essential for sensing the signaling from DNA double-strand breaks. Mirin is an inhibitor of MRN discovered using a forward chemical genetic screen. It prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity and it inhibits Mre11-associated exonuclease activity. IC50=66µM. It abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Formula:
C₁₀H₈N₂O₂S MW: 220.246 g/mol |
MDL Number:
MFCD05885480 CAS Number: 299953-00-7 |
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