Mirin ≥95% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: cis-5-(4-Hydroxybenzylidene)-2-imino-4-thiazolidinone

BML-GR357-0025 BML-GR357-0005
89158-994EA 452.36 USD
89158-994 89158-992
Mirin ≥95% (by TLC)
Mirin

MRN inhibitor


The MRN-ATM pathway is essential for sensing the signaling from DNA double-strand breaks. Mirin is an inhibitor of MRN discovered using a forward chemical genetic screen. It prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity and it inhibits Mre11-associated exonuclease activity. IC50=66µM. It abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.

Formula: C₁₀H₈N₂O₂S
MW: 220.246 g/mol
MDL Number: MFCD05885480
CAS Number: 299953-00-7
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