Chaetocin ≥98% (by TLC)

Supplier: Enzo Life Sciences

BML-GR349-0200
89158-986EA 118.08 USD
89158-986
Chaetocin ≥98% (by TLC)
Chaetocin

Methyltransferase inhibitor


Chaetocin, an antitumor antibiotic, is a thiodioxopiperazine natural product produced by Chaetomium species. Specific inhibitor of the lysine-specific methyltransferase SU (VAR)3-9 both in vitro and in vivo. It displays potent antimyeloma activity in IL-6-dependent myeloma cell lines. Its antimyeloma activity appears to be due to induction of oxidative stress and consequent apoptosis.


Isolated from Chaetomium sp-

CAS Number: 28097-03-2

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