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Apicidin ≥99% (by HPLC, TLC)

Supplier: Enzo Life Sciences
Synonyms: cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl]

BML-GR340-0001 GR340-0005
HDAC inhibitor

Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. At 100nM it induces a long lasting hyperacetylation of histone H4 while that induced by trichostatin is transient. Stimulates apoptosis. Apoptosis is induced via induction of Fas/Fas ligand. Displays potent antiangiogenic effects and dramatically decreases HIF-1α protein levels and transcriptional activity in human and mouse tumor cell lines. Antiprotozoal.


Formula: C₃₄H₄₉N₅O₆
MW: 623.8 g/mol
CAS Number: 183506-66-3


 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 mg BML-GR340-0001 89158-970 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

5 mg BML-GR340-0005 89158-972 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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VWR will not lift restrictions for residential shipping addresses.

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