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Troglitazone ≥98% (by TLC)

Supplier: Enzo Life Sciences

Troglitazone ≥98% (by TLC)

Troglitazone ≥98% (by TLC)

Synonyms: 5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy)benzyl)thiazolidine-2,4-dione

BML-GR210-0005 BML-GR210-0025

89158-796EA 611.56 USD

89158-796 89158-794

Troglitazone ≥98% (by TLC)

Troglitazone

PPAR ligand

Antidiabetic thiazolidinedione. Potent and selective PPARγ ligand. Binds to the PPARγ ligand-binding domain and recruits ligand-specific transcriptional coactivators at 1µM. In skeletal muscle and adipocyte cell cultures, the EC50 of troglitazone is about 10µM. Displaces [125I]SB-236636 with an IC50=7.9 µM. Stimulates adipogenesis and decreases osteoblastogenesis in human mesenchymal stem cells. Induces apoptosis in human vascular smooth muscle cells and inhibits the growth of a variety of human cancer cells including lung, bladder and myeloid leukemia cells.

Synthetic.

Formula: C₂₄H₂₇NO₅S
MW: 441.5 g/mol

MDL Number: MFCD00878416
CAS Number: 97322-87-7

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