Human Glucagon like Peptide 1

Supplier: Enzo Life Sciences
GP1437-0100
89158-720EA 206.12 USD
89158-720
Human Glucagon like Peptide 1
Proteins and Peptides
A predominant cleaved form of pro-glucagon found in the pancreas and central nervous system. It has been reported that human pancreatic endocrine tumours contain molecular forms of GLP-1 which resemble those expressed in the small intestine, rather than in their tissue of origin. Within the CNS, GLP-1 powerfully inhibits feeding in fasting rats, an action which is blocked by prior administration of the GLP-1 receptor antagonist exendin [9-39]. This observation led to the suggestion that central GLP-1 is a physiological mediator of satiety and has projected GLP-1 into the obesity control debate. Glucagon-like peptide (GLP) 1 [1-36] also serves as a control peptide for Anti-Glucagon-like Peptide (GLP) 1 (BML-GA1176) and Anti-Glucagon-like Peptide (GLP) 1 [7-36] amide (BML-GA1178). Blocks immunoreactivity at 10 nmol per ml diluted antibody.
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